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Targeting PI3K in cancer: mechanisms and advances in clinical trials
Phosphatidylinositol-3-kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) signaling is one of the most important intracellular pathways, which can be considered as a master regulator for cancer. Enormous efforts have been dedicated to the development of drugs targeting PI3K signaling, many of wh...
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| 出版年: | Mol Cancer |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6379961/ https://ncbi.nlm.nih.gov/pubmed/30782187 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-019-0954-x |
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