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Targeting epigenetic regulators for cancer therapy: mechanisms and advances in clinical trials
Epigenetic alternations concern heritable yet reversible changes in histone or DNA modifications that regulate gene activity beyond the underlying sequence. Epigenetic dysregulation is often linked to human disease, notably cancer. With the development of various drugs targeting epigenetic regulator...
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| 發表在: | Signal Transduct Target Ther |
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| Main Authors: | , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group UK
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6915746/ https://ncbi.nlm.nih.gov/pubmed/31871779 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41392-019-0095-0 |
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