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Targeting epigenetic regulators for cancer therapy: mechanisms and advances in clinical trials

Epigenetic alternations concern heritable yet reversible changes in histone or DNA modifications that regulate gene activity beyond the underlying sequence. Epigenetic dysregulation is often linked to human disease, notably cancer. With the development of various drugs targeting epigenetic regulator...

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Bibliografski detalji
Izdano u:Signal Transduct Target Ther
Glavni autori: Cheng, Yuan, He, Cai, Wang, Manni, Ma, Xuelei, Mo, Fei, Yang, Shengyong, Han, Junhong, Wei, Xiawei
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6915746/
https://ncbi.nlm.nih.gov/pubmed/31871779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41392-019-0095-0
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