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Targeting epigenetic regulators for cancer therapy: mechanisms and advances in clinical trials
Epigenetic alternations concern heritable yet reversible changes in histone or DNA modifications that regulate gene activity beyond the underlying sequence. Epigenetic dysregulation is often linked to human disease, notably cancer. With the development of various drugs targeting epigenetic regulator...
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| Publicado no: | Signal Transduct Target Ther |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6915746/ https://ncbi.nlm.nih.gov/pubmed/31871779 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41392-019-0095-0 |
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