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Targeting epigenetic regulators for cancer therapy: mechanisms and advances in clinical trials

Epigenetic alternations concern heritable yet reversible changes in histone or DNA modifications that regulate gene activity beyond the underlying sequence. Epigenetic dysregulation is often linked to human disease, notably cancer. With the development of various drugs targeting epigenetic regulator...

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Bibliografische gegevens
Gepubliceerd in:Signal Transduct Target Ther
Hoofdauteurs: Cheng, Yuan, He, Cai, Wang, Manni, Ma, Xuelei, Mo, Fei, Yang, Shengyong, Han, Junhong, Wei, Xiawei
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6915746/
https://ncbi.nlm.nih.gov/pubmed/31871779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41392-019-0095-0
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