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Molecular mechanisms of tumor resistance to PI3K-mTOR-targeted therapy
Deregulation of the phosphatidylinositide 3-kinase (PI3K) and mammalian target of rapamycin (mTOR) signaling pathway occurs frequently in a wide range of human cancers and is a major driving force in tumorigenesis. Thus, small molecules targeting this pathway are under active development as anticanc...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Sun Yat-sen University Cancer Center
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3845604/ https://ncbi.nlm.nih.gov/pubmed/23668928 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5732/cjc.012.10287 |
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