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Achieving cancer cell death with PI3K/mTOR-targeted therapies

Inhibitors of the PI3K/mTOR signaling network are under development as novel cancer therapies. However, these compounds do not cause robust cytotoxic responses in tumor cells unless combined with other agents. Rational combinations with other targeted therapies will likely be necessary to achieve th...

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Autors principals: Yea, Sung Su, Fruman, David A.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3621026/
https://ncbi.nlm.nih.gov/pubmed/23551096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nyas.12028
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