Recent advances in the use of PI3K inhibitors for glioblastoma multiforme: current preclinical and clinical development

Glioblastoma multiforme (GBM) is the most common and aggressive malignant primary tumor in the central nervous system. One of the most widely used chemotherapeutic drugs for GBM is temozolomide, which is a DNA-alkylating agent and its efficacy is dependent on MGMT methylation status. Little progress...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Mol Cancer
Asıl Yazarlar: Zhao, Hua-fu, Wang, Jing, Shao, Wei, Wu, Chang-peng, Chen, Zhong-ping, To, Shing-shun Tony, Li, Wei-ping
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2017
Konular:
Review
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5463420/
https://ncbi.nlm.nih.gov/pubmed/28592260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-017-0670-3
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