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Recent advances in the use of PI3K inhibitors for glioblastoma multiforme: current preclinical and clinical development

Glioblastoma multiforme (GBM) is the most common and aggressive malignant primary tumor in the central nervous system. One of the most widely used chemotherapeutic drugs for GBM is temozolomide, which is a DNA-alkylating agent and its efficacy is dependent on MGMT methylation status. Little progress...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Mol Cancer
Päätekijät: Zhao, Hua-fu, Wang, Jing, Shao, Wei, Wu, Chang-peng, Chen, Zhong-ping, To, Shing-shun Tony, Li, Wei-ping
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5463420/
https://ncbi.nlm.nih.gov/pubmed/28592260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-017-0670-3
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