cAMP-dependent activation of the Rac guanine exchange factor P-REX1 by type I protein kinase A (PKA) regulatory subunits

Regulatory subunits of protein kinase A (PKA) inhibit its kinase subunits. Intriguingly, their potential as cAMP-dependent signal transducers remains uncharacterized. We recently reported that type I PKA regulatory subunits (RIα) interact with phosphatidylinositol 3,4,5-trisphosphate–dependent Rac e...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Biol Chem
Prif Awduron: Adame-García, Sendi Rafael, Cervantes-Villagrana, Rodolfo Daniel, Orduña-Castillo, Lennis Beatriz, del Rio, Jason C., Gutkind, J. Silvio, Reyes-Cruz, Guadalupe, Taylor, Susan S., Vázquez-Prado, José
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2019
Pynciau:
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Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6378977/
https://ncbi.nlm.nih.gov/pubmed/30530493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006691
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