Protein Kinase A (PKA) Type I Interacts with P-Rex1, a Rac Guanine Nucleotide Exchange Factor: EFFECT ON PKA LOCALIZATION AND P-Rex1 SIGNALING

Morphology of migrating cells is regulated by Rho GTPases and fine-tuned by protein interactions and phosphorylation. PKA affects cell migration potentially through spatiotemporal interactions with regulators of Rho GTPases. Here we show that the endogenous regulatory (R) subunit of type I PKA inter...

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Veröffentlicht in:J Biol Chem
Hauptverfasser: Chávez-Vargas, Lydia, Adame-García, Sendi Rafael, Cervantes-Villagrana, Rodolfo Daniel, Castillo-Kauil, Alejandro, Bruystens, Jessica G. H., Fukuhara, Shigetomo, Taylor, Susan S., Mochizuki, Naoki, Reyes-Cruz, Guadalupe, Vázquez-Prado, José
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2016
Schlagworte:
Signal Transduction
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813559/
https://ncbi.nlm.nih.gov/pubmed/26797121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.712216
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