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Rhodium-Catalyzed Aldehyde Arylation via Formate-Mediated Transfer Hydrogenation: Beyond Metallic Reductants in Grignard-NHK-Type Addition

The first intermolecular carbonyl arylations via transfer hydrogenative reductive coupling are described. Using rhodium catalysts modified by (t)Bu(2)PMe, sodium formate-mediated reductive coupling of aryl iodides with aldehydes occurs in a chemoselective fashion in the presence of protic functional...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Swyka, Robert A., Zhang, Wandi, Richardson, Jeffery, Ruble, J. Craig, Krische, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6376962/
https://ncbi.nlm.nih.gov/pubmed/30693768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b13652
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