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Pharmacogenetics and pharmacokinetics of CNS penetration of efavirenz and its metabolites
BACKGROUND: There are limited data on the pharmacogenetics and pharmacokinetics of the CNS penetration of efavirenz. OBJECTIVES: We investigated genetic polymorphisms associated with CSF concentrations of efavirenz and its metabolites and explored the relationships with neurocognitive performance. M...
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| Veröffentlicht in: | J Antimicrob Chemother |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6376850/ https://ncbi.nlm.nih.gov/pubmed/30535366 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dky481 |
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