An ATF6-tPA pathway in hepatocytes contributes to systemic fibrinolysis and is repressed by DACH1

Tissue-type plasminogen activator (tPA) is a major mediator of fibrinolysis and, thereby, prevents excessive coagulation without compromising hemostasis. Studies on tPA regulation have focused on its acute local release by vascular cells in response to injury or other stimuli. However, very little i...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Blood
Autori principali: Zheng, Ze, Nayak, Lalitha, Wang, Wei, Yurdagul, Arif, Wang, Xiaobo, Cai, Bishuang, Lapping, Stephanie, Ozcan, Lale, Ramakrishnan, Rajasekhar, Pestell, Richard G., Jain, Mukesh K., Tabas, Ira
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2019
Soggetti:
Thrombosis and Hemostasis
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6376283/
https://ncbi.nlm.nih.gov/pubmed/30504459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2018-07-864843
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi