Carbonic anhydrase is not a relevant nitrite reductase or nitrous anhydrase in the lung

KEY POINTS: Carbonic anhydrase (CA) inhibitors such as acetazolamide inhibit hypoxic pulmonary vasoconstriction (HPV) in humans and other mammals, but the mechanism of this action remains unknown. It has been postulated that carbonic anhydrase may act as a nitrous anhydrase in vivo to generate nitri...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Physiol
Päätekijät: Pickerodt, Philipp A., Kronfeldt, Sebastian, Russ, Martin, Gonzalez‐Lopez, Adrian, Lother, Philipp, Steiner, Elvira, Vorbrodt, Katja, Busch, Thilo, Boemke, Willehad, Francis, Roland C. E., Swenson, Erik R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2018
Aiheet:
Reviews and Research Papers
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6376076/
https://ncbi.nlm.nih.gov/pubmed/29660141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP275894
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