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Lavage-induced Surfactant Depletion in Pigs As a Model of the Acute Respiratory Distress Syndrome (ARDS)

Various animal models of lung injury exist to study the complex pathomechanisms of human acute respiratory distress syndrome (ARDS) and evaluate future therapies. Severe lung injury with a reproducible deterioration of pulmonary gas exchange and hemodynamics can be induced in anesthetized pigs using...

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Publicat a:J Vis Exp
Autors principals: Russ, Martin, Kronfeldt, Sebastian, Boemke, Willehad, Busch, Thilo, Francis, Roland C. E., Pickerodt, Philipp A.
Format: Artigo
Idioma:Inglês
Publicat: MyJove Corporation 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5091986/
https://ncbi.nlm.nih.gov/pubmed/27684585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/53610
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