Effects of living at moderate altitude on pulmonary vascular function and exercise capacity in mice with sickle cell anaemia

KEY POINTS: Sickle cell disease (SCD) results in cardiopulmonary dysfunction, which may be exacerbated by prolonged exposure to environmental hypoxia. It is currently unknown whether exposure to mild and moderate altitude exacerbates SCD associated cardiopulmonary and systemic complications. Three m...

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Publicado en:J Physiol
Main Authors: Ferguson, Scott K., Redinius, Katherine, Yalamanoglu, Ayla, Harral, Julie W., Hyen Baek, Jin, Pak, David, Loomis, Zoe, Hassell, Daniel, Eigenberger, Paul, Nozik‐Grayck, Eva, Nuss, Rachelle, Hassell, Kathryn, Stenmark, Kurt R., Buehler, Paul W., Irwin, David C.
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2018
Assuntos:
Reviews and research papers
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6376072/
https://ncbi.nlm.nih.gov/pubmed/29931797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP275810
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