Hemoglobin induced lung vascular oxidation, inflammation, and remodeling contributes to the progression of hypoxic pulmonary hypertension and is attenuated in rats with repeat dose haptoglobin administration

OBJECTIVE: Haptoglobin (Hp) is an approved treatment in Japan with indications for trauma, burns and massive transfusion related hemolysis. Additional case reports suggest uses in other acute hemolytic events that lead to acute kidney injury. However, Hp's protective effects on the pulmonary va...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Free Radic Biol Med
Main Authors: Irwin, David C., Baek, Jin Hyen, Hassell, Kathryn, Nuss, Rachelle, Eigenberger, Paul, Lisk, Christina, Loomis, Zoe, Maltzahn, Joanne, Stenmark, Kurt R, Nozik-Grayck, Eva, Buehler, Paul W.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4387123/
https://ncbi.nlm.nih.gov/pubmed/25656991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2015.01.012
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares