Transition from post‐capillary pulmonary hypertension to combined pre‐ and post‐capillary pulmonary hypertension in swine: a key role for endothelin

KEY POINTS: Passive, isolated post‐capillary pulmonary hypertension (PH) secondary to left heart disease may progress to combined pre‐ and post‐capillary or ‘active’ PH. This ‘activation’ of post‐capillary PH significantly increases morbidity and mortality, and is still incompletely understood. In t...

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Bibliographic Details
Published in:J Physiol
Main Authors: van Duin, Richard W. B., Stam, Kelly, Cai, Zongye, Uitterdijk, André, Garcia‐Alvarez, Ana, Ibanez, Borja, Danser, A. H. Jan, Reiss, Irwin K. M., Duncker, Dirk J., Merkus, Daphne
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2018
Subjects:
Reviews and Research Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6375874/
https://ncbi.nlm.nih.gov/pubmed/29799120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP275987
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