Transition from post‐capillary pulmonary hypertension to combined pre‐ and post‐capillary pulmonary hypertension in swine: a key role for endothelin

KEY POINTS: Passive, isolated post‐capillary pulmonary hypertension (PH) secondary to left heart disease may progress to combined pre‐ and post‐capillary or ‘active’ PH. This ‘activation’ of post‐capillary PH significantly increases morbidity and mortality, and is still incompletely understood. In t...

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Detalhes bibliográficos
Publicado no:J Physiol
Main Authors: van Duin, Richard W. B., Stam, Kelly, Cai, Zongye, Uitterdijk, André, Garcia‐Alvarez, Ana, Ibanez, Borja, Danser, A. H. Jan, Reiss, Irwin K. M., Duncker, Dirk J., Merkus, Daphne
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Reviews and Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6375874/
https://ncbi.nlm.nih.gov/pubmed/29799120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP275987
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