Transition from post‐capillary pulmonary hypertension to combined pre‐ and post‐capillary pulmonary hypertension in swine: a key role for endothelin

KEY POINTS: Passive, isolated post‐capillary pulmonary hypertension (PH) secondary to left heart disease may progress to combined pre‐ and post‐capillary or ‘active’ PH. This ‘activation’ of post‐capillary PH significantly increases morbidity and mortality, and is still incompletely understood. In t...

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Bibliografiske detaljer
Udgivet i:J Physiol
Main Authors: van Duin, Richard W. B., Stam, Kelly, Cai, Zongye, Uitterdijk, André, Garcia‐Alvarez, Ana, Ibanez, Borja, Danser, A. H. Jan, Reiss, Irwin K. M., Duncker, Dirk J., Merkus, Daphne
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2018
Fag:
Reviews and Research Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6375874/
https://ncbi.nlm.nih.gov/pubmed/29799120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP275987
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