Transition from post‐capillary pulmonary hypertension to combined pre‐ and post‐capillary pulmonary hypertension in swine: a key role for endothelin

KEY POINTS: Passive, isolated post‐capillary pulmonary hypertension (PH) secondary to left heart disease may progress to combined pre‐ and post‐capillary or ‘active’ PH. This ‘activation’ of post‐capillary PH significantly increases morbidity and mortality, and is still incompletely understood. In t...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Physiol
Auteurs principaux: van Duin, Richard W. B., Stam, Kelly, Cai, Zongye, Uitterdijk, André, Garcia‐Alvarez, Ana, Ibanez, Borja, Danser, A. H. Jan, Reiss, Irwin K. M., Duncker, Dirk J., Merkus, Daphne
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2018
Sujets:
Reviews and Research Papers
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6375874/
https://ncbi.nlm.nih.gov/pubmed/29799120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP275987
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