RANKL Inhibits the Production of Osteoprotegerin from Smooth Muscle Cells under Basal Conditions and following Exposure to Cyclic Strain

Receptor activator of nuclear factor-κB ligand (RANKL) promotes vascular calcification, while osteoprotegerin (OPG) opposes it by blocking RANKL activity. It remains unclear which vascular cell populations produce and secrete OPG/RANKL. This study characterizes the production of OPG/RANKL from human...

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Vydáno v:J Vasc Res
Hlavní autoři: Davenport, Colin, Harper, Emma, Rochfort, Keith D., Forde, Hannah, Smith, Diarmuid, Cummins, Philip M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6375687/
https://ncbi.nlm.nih.gov/pubmed/29635231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000486787
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