Activation of the non-canonical NF-κB/p52 pathway in vascular endothelial cells by RANKL elicits pro-calcific signalling in co-cultured smooth muscle cells

BACKGROUND: The intimal endothelium is known to condition the underlying medial smooth muscle cell (SMC) layer of the vessel wall, and is highly responsive to receptor-activator of nuclear factor-kB ligand (RANKL) and tumour necrosis factor-related apoptosis-inducing ligand (TRAIL), pro-calcific and...

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Vydáno v:Cell Signal
Hlavní autoři: Harper, Emma, Rochfort, Keith D., Forde, Hannah, Davenport, Colin, Smith, Diarmuid, Cummins, Philip M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6376867/
https://ncbi.nlm.nih.gov/pubmed/29678621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2018.04.004
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