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TRAIL attenuates RANKL-mediated osteoblastic signalling in vascular cell mono-culture and co-culture models

BACKGROUND AND OBJECTIVES: Vascular calcification (VC) is a major risk factor for elevated cardiovascular morbidity/mortality. Underlying this process is osteoblastic signalling within the vessel wall involving complex and interlinked roles for receptor-activator of nuclear factor-κB ligand (RANKL),...

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Publicat a:PLoS One
Autors principals: Harper, Emma, Rochfort, Keith D., Forde, Hannah, Davenport, Colin, Smith, Diarmuid, Cummins, Philip M.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5690591/
https://ncbi.nlm.nih.gov/pubmed/29145460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0188192
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