Regulation of Thrombomodulin Expression and Release in Human Aortic Endothelial Cells by Cyclic Strain

BACKGROUND AND OBJECTIVES: Thrombomodulin (TM), an integral membrane glycoprotein expressed on the lumenal surface of vascular endothelial cells, promotes anti-coagulant and anti-inflammatory properties. Release of functional TM from the endothelium surface into plasma has also been reported. Much i...

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Detalhes bibliográficos
Principais autores: Martin, Fiona A., McLoughlin, Alisha, Rochfort, Keith D., Davenport, Colin, Murphy, Ronan P., Cummins, Philip M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169621/
https://ncbi.nlm.nih.gov/pubmed/25238231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0108254
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