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Lens differentiation is controlled by the balance between PDGF and FGF signaling
How multiple receptor tyrosine kinases coordinate cell fate determination is yet to be elucidated. We show here that the receptor for platelet-derived growth factor (PDGF) signaling recruits the p85 subunit of Phosphoinositide 3-kinase (PI3K) to regulate mammalian lens development. Activation of PI3...
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| 出版年: | PLoS Biol |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6375662/ https://ncbi.nlm.nih.gov/pubmed/30716082 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000133 |
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