Etv transcription factors functionally diverge from their upstream FGF signaling in lens development

The signal regulated transcription factors (SRTFs) control the ultimate transcriptional output of signaling pathways. Here, we examined a family of FGF-induced SRTFs – Etv1, Etv 4, and Etv 5 – in murine lens development. Contrary to FGF receptor mutants that displayed loss of ERK signaling and defec...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Garg, Ankur, Hannan, Abdul, Wang, Qian, Makrides, Neoklis, Zhong, Jian, Li, Hongge, Yoon, Sungtae, Mao, Yingyu, Zhang, Xin
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2020
Assuntos:
Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7069720/
https://ncbi.nlm.nih.gov/pubmed/32043969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.51915
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