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Deficient FGF signaling causes optic nerve dysgenesis and ocular coloboma

FGF signaling plays a pivotal role in eye development. Previous studies using in vitro chick models and systemic zebrafish mutants have suggested that FGF signaling is required for the patterning and specification of the optic vesicle, but due to a lack of genetic models, its role in mammalian retin...

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Détails bibliographiques
Auteurs principaux: Cai, Zhigang, Tao, Chenqi, Li, Hongge, Ladher, Raj, Gotoh, Noriko, Feng, Gen-Sheng, Wang, Fen, Zhang, Xin
Format: Artigo
Langue:Inglês
Publié: Company of Biologists 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3678341/
https://ncbi.nlm.nih.gov/pubmed/23720040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.089987
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