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Deficient FGF signaling causes optic nerve dysgenesis and ocular coloboma
FGF signaling plays a pivotal role in eye development. Previous studies using in vitro chick models and systemic zebrafish mutants have suggested that FGF signaling is required for the patterning and specification of the optic vesicle, but due to a lack of genetic models, its role in mammalian retin...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Company of Biologists
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3678341/ https://ncbi.nlm.nih.gov/pubmed/23720040 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.089987 |
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