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Deficient FGF signaling causes optic nerve dysgenesis and ocular coloboma

FGF signaling plays a pivotal role in eye development. Previous studies using in vitro chick models and systemic zebrafish mutants have suggested that FGF signaling is required for the patterning and specification of the optic vesicle, but due to a lack of genetic models, its role in mammalian retin...

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Detalles Bibliográficos
Main Authors: Cai, Zhigang, Tao, Chenqi, Li, Hongge, Ladher, Raj, Gotoh, Noriko, Feng, Gen-Sheng, Wang, Fen, Zhang, Xin
Formato: Artigo
Idioma:Inglês
Publicado: Company of Biologists 2013
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3678341/
https://ncbi.nlm.nih.gov/pubmed/23720040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.089987
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