Conformational regulation of Escherichia coli DNA polymerase V by RecA and ATP

Mutagenic translesion DNA polymerase V (UmuD′(2)C) is induced as part of the DNA damage-induced SOS response in Escherichia coli, and is subjected to multiple levels of regulation. The UmuC subunit is sequestered on the cell membrane (spatial regulation) and enters the cytosol after forming a UmuD′(...

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Détails bibliographiques
Publié dans:PLoS Genet
Auteurs principaux: Jaszczur, Malgorzata M., Vo, Dan D., Stanciauskas, Ramunas, Bertram, Jeffrey G., Sikand, Adhirath, Cox, Michael M., Woodgate, Roger, Mak, Chi H., Pinaud, Fabien, Goodman, Myron F.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2019
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6375631/
https://ncbi.nlm.nih.gov/pubmed/30716079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007956
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