Conformational regulation of Escherichia coli DNA polymerase V by RecA and ATP

Mutagenic translesion DNA polymerase V (UmuD′(2)C) is induced as part of the DNA damage-induced SOS response in Escherichia coli, and is subjected to multiple levels of regulation. The UmuC subunit is sequestered on the cell membrane (spatial regulation) and enters the cytosol after forming a UmuD′(...

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Publicado en:PLoS Genet
Main Authors: Jaszczur, Malgorzata M., Vo, Dan D., Stanciauskas, Ramunas, Bertram, Jeffrey G., Sikand, Adhirath, Cox, Michael M., Woodgate, Roger, Mak, Chi H., Pinaud, Fabien, Goodman, Myron F.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2019
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6375631/
https://ncbi.nlm.nih.gov/pubmed/30716079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007956
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