Conformational regulation of Escherichia coli DNA polymerase V by RecA and ATP

Mutagenic translesion DNA polymerase V (UmuD′(2)C) is induced as part of the DNA damage-induced SOS response in Escherichia coli, and is subjected to multiple levels of regulation. The UmuC subunit is sequestered on the cell membrane (spatial regulation) and enters the cytosol after forming a UmuD′(...

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Vydáno v:PLoS Genet
Hlavní autoři: Jaszczur, Malgorzata M., Vo, Dan D., Stanciauskas, Ramunas, Bertram, Jeffrey G., Sikand, Adhirath, Cox, Michael M., Woodgate, Roger, Mak, Chi H., Pinaud, Fabien, Goodman, Myron F.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2019
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6375631/
https://ncbi.nlm.nih.gov/pubmed/30716079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007956
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