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Insulin Receptor deletion in S100a4-lineage cells accelerates age-related bone loss
Type I and Type II Diabetes dramatically impair skeletal health. Altered Insulin Receptor (IR) signaling is a common feature of both diseases, and insulin has potent bone anabolic functions. Several previous studies have demonstrated that loss of IR in bone cells results in disrupted bone homeostasi...
Enregistré dans:
| Publié dans: | Bone Rep |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Elsevier
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6374520/ https://ncbi.nlm.nih.gov/pubmed/30805422 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bonr.2019.100197 |
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