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Deletion of EP4 in S100a4-lineage cells reduces scar tissue formation during early but not later stages of tendon healing

Tendon injuries heal via scar tissue rather than regeneration. This healing response forms adhesions between the flexor tendons in the hand and surrounding tissues, resulting in impaired range of motion and hand function. Mechanistically, inflammation has been strongly linked to adhesion formation,...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Ackerman, Jessica E., Best, Katherine T., O’Keefe, Regis J., Loiselle, Alayna E.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5561254/
https://ncbi.nlm.nih.gov/pubmed/28819185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-09407-7
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