Deletion of PPARγ in Mesenchymal Lineage Cells Protects Against Aging-Induced Cortical Bone Loss in Mice

Bone loss in aging is linked with chronic low-grade inflammation and the accumulation of marrowfat in animals and humans. Peroxisome proliferator-activated receptor gamma (PPARγ), an adipogenic regulator, plays key roles in these biological processes. However, studies of the roles of PPARγ in age-re...

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Gepubliceerd in:J Gerontol A Biol Sci Med Sci
Hoofdauteurs: Cao, Jay, Ding, Kehong, Pan, Guodong, Rosario, Raysa, Su, Yun, Bao, Yonggang, Zhou, Hongyan, Xu, Jianru, McGee Lawrence, Meghan E, Hamrick, Mark W, Isales, Carlos M, Shi, Xingming
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2020
Onderwerpen:
THE JOURNAL OF GERONTOLOGY: Biological Sciences
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7164529/
https://ncbi.nlm.nih.gov/pubmed/32060555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glaa049
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