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Effect of PPARγ Inhibition on Bone in Aged Animals

Aging is accompanied by bone loss and marrowfat accumulation. PPARg is a key factor regulating adipocyte differentiation. Marrowfat secretes large quantities of factors including adipokines, cytokines and chemokines that contribute to bone loss. We hypothesized that inhibition of PPARg would reduce...

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Bibliografiske detaljer
Udgivet i:Innov Aging
Main Authors: Shi, Xingming, Ding, Kehong, Su, Yun, Isales, Carlos
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7740238/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igaa057.408
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