Loss of the PGE2 Receptor EP1 enhances bone acquisition, which protects against age and ovariectomy-induced impairments in bone strength

PGE2 exerts anabolic and catabolic effects on bone through the discrete actions of four prostanoid receptors (EP1-4). We have previously demonstrated that loss EP1 accelerates fracture repair by enhancing bone formation. In the present study we defined the role of EP1 in bone maintenance and homeost...

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Publicado no:Bone
Main Authors: Zhang, Minjie, Feigenson, Marina, Sheu, Tzong-jen, Awad, Hani A., Schwarz, Edward M., Jonason, Jennifer H., Loiselle, Alayna E., O’Keefe, Regis J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4437532/
https://ncbi.nlm.nih.gov/pubmed/25446888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2014.11.018
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