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Compartmentalized Cyclic Nucleotides Have Opposing Effects on Regulation of Hypertrophic Phospholipase Cε Signaling in Cardiac Myocytes
In cardiac myocytes activation of an exchange factor activated by cAMP (Epac) leads to activation of phospholipase Cε (PLCε)-dependent hydrolysis of phosphatidylinositol 4-phosphate (PI4P) in the Golgi apparatus a process critical for development of cardiac hypertrophy. Here we show that β-adrenergi...
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| Yayımlandı: | J Mol Cell Cardiol |
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| Asıl Yazarlar: | , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2018
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6373484/ https://ncbi.nlm.nih.gov/pubmed/29885334 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2018.06.002 |
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