Effect of Immediate vs Gradual Reduction in Nicotine Content of Cigarettes on Biomarkers of Smoke Exposure: A Randomized Clinical Trial

IMPORTANCE: The optimal temporal approach for reducing nicotine to minimally or nonaddictive levels in all cigarettes sold in the United States has not been determined. OBJECTIVES: To determine the effects of immediate vs gradual reduction in nicotine content to very low levels and as compared with...

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Publicado en:JAMA
Autores principales: Hatsukami, Dorothy K., Luo, Xianghua, Jensen, Joni A., al’Absi, Mustafa, Allen, Sharon S., Carmella, Steven G., Chen, Menglan, Cinciripini, Paul M., Denlinger-Apte, Rachel, Drobes, David J., Koopmeiners, Joseph S., Lane, Tonya, Le, Chap T., Leischow, Scott, Luo, Kai, McClernon, F. Joseph, Murphy, Sharon E., Paiano, Viviana, Robinson, Jason D., Severson, Herbert, Sipe, Christopher, Strasser, Andrew A., Strayer, Lori G., Tang, Mei Kuen, Vandrey, Ryan, Hecht, Stephen S., Benowitz, Neal L., Donny, Eric C.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6372240/
https://ncbi.nlm.nih.gov/pubmed/30193275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2018.11473
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