TP53 gain-of-function mutation promotes inflammation in glioblastoma

Glioblastoma (GBM), the most severe and common brain tumor in adults, is characterized by multiple somatic mutations and aberrant activation of inflammatory responses. Immune cell infiltration and subsequent inflammation cause tumor growth and resistance to therapy. Somatic loss-of-function mutation...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Death Differ
Prif Awduron: Ham, Seok Won, Jeon, Hee-Young, Jin, Xiong, Kim, Eun-Jung, Kim, Jun-Kyum, Shin, Yong Jae, Lee, Yeri, Kim, Se Hoon, Lee, Seon Yong, Seo, Sunyoung, Park, Min Gi, Kim, Hye-Mi, Nam, Do-Hyun, Kim, Hyunggee
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2018
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6370770/
https://ncbi.nlm.nih.gov/pubmed/29786075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-018-0126-3
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