TP53 gain-of-function mutation promotes inflammation in glioblastoma

Glioblastoma (GBM), the most severe and common brain tumor in adults, is characterized by multiple somatic mutations and aberrant activation of inflammatory responses. Immune cell infiltration and subsequent inflammation cause tumor growth and resistance to therapy. Somatic loss-of-function mutation...

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Publicat a:Cell Death Differ
Autors principals: Ham, Seok Won, Jeon, Hee-Young, Jin, Xiong, Kim, Eun-Jung, Kim, Jun-Kyum, Shin, Yong Jae, Lee, Yeri, Kim, Se Hoon, Lee, Seon Yong, Seo, Sunyoung, Park, Min Gi, Kim, Hye-Mi, Nam, Do-Hyun, Kim, Hyunggee
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6370770/
https://ncbi.nlm.nih.gov/pubmed/29786075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-018-0126-3
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