Ly6G(+) inflammatory cells enable the conversion of cancer cells to cancer stem cells in an irradiated glioblastoma model

Most glioblastomas frequently recur at sites of radiotherapy, but it is unclear if changes in the tumor microenvironment due to radiotherapy influence glioblastoma recurrence. Here, we demonstrate that radiation-induced senescent glioblastoma cells exhibit a senescence-associated secretory phenotype...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Jeon, Hee-Young, Ham, Seok Won, Kim, Jun-Kyum, Jin, Xiong, Lee, Seon Yong, Shin, Yong Jae, Choi, Chang-Yong, Sa, Jason K., Kim, Se Hoon, Chun, Taehoon, Jin, Xun, Nam, Do-Hyun, Kim, Hyunggee
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6748155/
https://ncbi.nlm.nih.gov/pubmed/30804471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-019-0282-0
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