Ly6G(+) inflammatory cells enable the conversion of cancer cells to cancer stem cells in an irradiated glioblastoma model

Most glioblastomas frequently recur at sites of radiotherapy, but it is unclear if changes in the tumor microenvironment due to radiotherapy influence glioblastoma recurrence. Here, we demonstrate that radiation-induced senescent glioblastoma cells exhibit a senescence-associated secretory phenotype...

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Publicat a:Cell Death Differ
Autors principals: Jeon, Hee-Young, Ham, Seok Won, Kim, Jun-Kyum, Jin, Xiong, Lee, Seon Yong, Shin, Yong Jae, Choi, Chang-Yong, Sa, Jason K., Kim, Se Hoon, Chun, Taehoon, Jin, Xun, Nam, Do-Hyun, Kim, Hyunggee
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6748155/
https://ncbi.nlm.nih.gov/pubmed/30804471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-019-0282-0
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