TP53 gain-of-function mutation promotes inflammation in glioblastoma

Glioblastoma (GBM), the most severe and common brain tumor in adults, is characterized by multiple somatic mutations and aberrant activation of inflammatory responses. Immune cell infiltration and subsequent inflammation cause tumor growth and resistance to therapy. Somatic loss-of-function mutation...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Ham, Seok Won, Jeon, Hee-Young, Jin, Xiong, Kim, Eun-Jung, Kim, Jun-Kyum, Shin, Yong Jae, Lee, Yeri, Kim, Se Hoon, Lee, Seon Yong, Seo, Sunyoung, Park, Min Gi, Kim, Hye-Mi, Nam, Do-Hyun, Kim, Hyunggee
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6370770/
https://ncbi.nlm.nih.gov/pubmed/29786075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-018-0126-3
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