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Chemical Space of Escherichia coli Dihydrofolate Reductase Inhibitors: New Approaches for Discovering Novel Drugs for Old Bugs

Given the alarming rise in instances of antibiotic resistance displayed by disease-causing microorganisms, it is necessary to accelerate efforts to find new antibiotic agents. One prominent approach is to identify potent inhibitors of receptors that are indispensable for the microorganism’s survival...

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Dettagli Bibliografici
Pubblicato in:Med Res Rev
Autori principali: Srinivasan, Bharath, Tonddast-Navaei, Sam, Roy, Ambrish, Zhou, Hongyi, Skolnick, Jeffrey
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6370515/
https://ncbi.nlm.nih.gov/pubmed/30192413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/med.21538
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