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Discovery and optimization of inhibitors of the Parkinson’s disease associated protein DJ-1
DJ-1 is a Parkinson’s disease associated protein endowed with enzymatic, redox sensing, regulatory, chaperoning, and neuroprotective activities. Although DJ-1 has been vigorously studied for the last decade and a half, its exact role in the progression of the disease remains uncertain. In addition,...
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| Publicado en: | ACS Chem Biol |
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| Autores principales: | , , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6370461/ https://ncbi.nlm.nih.gov/pubmed/30063823 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.8b00701 |
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