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Discovery and characterization of natural tropolones as inhibitors of the antibacterial target CapF from Staphylococcus aureus

The rapid spread of antibiotic-resistance among pathogenic bacteria poses a serious risk for public health. The search for novel therapeutic strategies and antimicrobial compounds is needed to ameliorate this menace. The bifunctional metalloenzyme CapF is an antibacterial target produced by certain...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Nakano, Koichiro, Chigira, Takeru, Miyafusa, Takamitsu, Nagatoishi, Satoru, Caaveiro, Jose M. M., Tsumoto, Kouhei
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5393024/
https://ncbi.nlm.nih.gov/pubmed/26471247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15337
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