Discovery and characterization of natural tropolones as inhibitors of the antibacterial target CapF from Staphylococcus aureus

The rapid spread of antibiotic-resistance among pathogenic bacteria poses a serious risk for public health. The search for novel therapeutic strategies and antimicrobial compounds is needed to ameliorate this menace. The bifunctional metalloenzyme CapF is an antibacterial target produced by certain...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Nakano, Koichiro, Chigira, Takeru, Miyafusa, Takamitsu, Nagatoishi, Satoru, Caaveiro, Jose M. M., Tsumoto, Kouhei
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5393024/
https://ncbi.nlm.nih.gov/pubmed/26471247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15337
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