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Ixazomib promotes CHOP-dependent DR5 induction and apoptosis in colorectal cancer cells

Background: Ixazomib (Ninlaro), a novel proteasome inhibitor, has been developed for the treatment of many cancers and has demonstrated anti-tumor efficacy against various malignancies. However, the mechanism of the anti-tumor effect of ixazomib in colorectal cancer (CRC) cells remains unclear. Meth...

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Detalles Bibliográficos
Publicado en:Cancer Biol Ther
Main Authors: Yue, Dan, Sun, Xun
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6370389/
https://ncbi.nlm.nih.gov/pubmed/30359552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2018.1529095
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