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Evolutionary Potential of Cis-Regulatory Mutations to Cause Rapid Changes in Transcription Factor Binding

Transcriptional regulation is crucial for all biological processes and well investigated at the molecular level for a wide range of organisms. However, it is quite unclear how innovations, such as the activity of a novel regulatory element, evolve. In the case of transcription factor (TF) binding, b...

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Détails bibliographiques
Publié dans:Genome Biol Evol
Auteurs principaux: Kurafeiski, Jasmin D, Pinto, Paulo, Bornberg-Bauer, Erich
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6370388/
https://ncbi.nlm.nih.gov/pubmed/30597011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evy269
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