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Nucleoprotein intermediates in HIV-1 DNA integration: structure and function of HIV-1 intasomes

Integration of a DNA copy of the viral genome into host DNA is an essential step in the replication cycle HIV-1 and other retroviruses and is an important therapeutic target for drugs. DNA integration is catalyzed by the viral integrase protein and proceeds through a series of stable nucleoprotein c...

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Detalhes bibliográficos
Publicado no:Subcell Biochem
Autor principal: Craigie, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6370045/
https://ncbi.nlm.nih.gov/pubmed/29900498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-981-10-8456-0_9
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