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Nucleoprotein intermediates in HIV-1 DNA integration visualized by atomic force microscopy

Integration of HIV-1 DNA into the genome of the host cell is an essential step in the viral replication cycle that is mediated by the virally encoded integrase protein. We have used atomic force microscopy to study stable complexes formed between HIV-1 integrase and viral DNA and their interaction w...

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書誌詳細
主要な著者: Kotova, Svetlana, Li, Min, Dimitriadis, Emilios K., Craigie, Robert
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3142783/
https://ncbi.nlm.nih.gov/pubmed/20416324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.04.026
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