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Visualization of DNA and Protein-DNA Complexes with Atomic Force Microscopy
This article describes sample preparation techniques for AFM imaging of DNA and protein–DNA complexes. The approach is based on chemical functionalization of the mica surface with aminopropyl silatrane (APS) to yield an APS-mica surface. This surface binds nucleic acids and nucleoprotein complexes i...
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| Publié dans: | Methods Mol Biol |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4226758/ https://ncbi.nlm.nih.gov/pubmed/24357372 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-62703-776-1_17 |
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